Neuronal Signaling

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Catalog No. Product Name Application Product Information


GABAA antagonist
(+)-Bicuculline is a classical GABAA antagonist.
A12761 SALE

(+)-MK 801 Maleate

NMDA receptor antagonist
(+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM.
A12043 SALE


COX-1 inhibitor
(-)-Epicatechin is a natural product from green tea. (-)Epicatechin is an inhibitor of Cox-1
A13435 SALE

(-)-MK 801 maleate

NMDA receptor antagonist.
(-)-MK 801 maleate acts as a potent, selective, and non-competitive NMDA receptor antagonist. It acts by binding to a site located within the NMDA associated ion channel.

(-)-Nicotine ditartrate

(-)-Nicotine ditartrate is a potent agonist of AChR (nicotinic acetylcholine recepto).
A12434 SALE


COX inhibitor
(S)-(+)-Flurbiprofen is a non-selective Cox-1 and Cox-2 inhibitor.


GABAB receptors antagonist
2-Hydroxysaclofen is a potent and selective antagonist at GABAB receptors.
A11166 SALE

5-hydroxymethyl tolterodine (PNU 200577)

muscarinic receptor antagonist

5-hydroxymethyl tolterodine is a metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.


A 438079 hydrochloride

P2X7 receptor antagonist
A 438079 Hcl is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line).
A11316 SALE

A 740003

P2X7 receptor antagonist
A 740003 is a novel competitive antagonist of P2X7 receptors (IC50 values = 40 nM for human and 18 nM for rat).

A-317491 sodium salt hydrate

P2X3 and P2X2/3 receptor antagonist
A-317491 sodium salt hydrate is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.


α7 nAChR agonist
A-582941 is a selective AChR a7 partial agonist. It exhibits high affinity for both rat and human a7 receptors (Ki values are 10.8 and 16.7 nM, respectively).
A16066 SALE


P2X7 receptor antagonist
A-804598 is a P2X7 selective, competitive antagonist with the IC50s value for human, rat and mouse channels of 11, 10 and 9 nM, respectively.


modulator of α7 nAChRs
A-867744 is a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor.
A11692 SALE

Acemetacin (Emflex)

Acemetacin is a glycolic acid ester of indometacin. It is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects.
A10030 SALE


COX inhibitor

Acetylcholine iodide

Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

Acotiamide hydrochloride trihydrate

Acetylcholinesterase inhibitor
Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.


P2X3/P2X2/3 receptor antagonist
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).

alpha-Amyloid Precursor Protein Modulator


Amfenac Sodium Monohydrate

COX inhibitor
Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.


Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 ??M.


COX inhibitor
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

Amyloid b-Peptide (1-40) (human)

Amyloid b-Peptide (1-40) (human) is a peptide processed from the amyloid precursor protein (APP).

Amyloid b-peptide (1-40) (rat)

Amyloid b-peptide (1-40) (rat)

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