MAPK
MAPK, also called Mitogen-activated protein kinases, are serine based protein kinases that respond to extracellular mitogens.
Targets for MAPK
New MAPK Inhibitors
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A11296 AS 602801 (Bentamapimod)
AS 602801 is a novel, orally active, Jun Kinase Inhibitor. -
A10089 AS703026
AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation. -
A10092 Asiatic acid
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. Asiatic acid derivative synthesis can be used as Anticancer agents; Glycogen phosphorylase inhibitors; Hepatoprotectants.
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A12021 Asiaticoside
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns. -
A11063 AZ628
AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF. -
A10257 AZD6244 (Selumetinib)
AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
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A10115 AZD8330
AZD8330 is a MEK inhibitor that specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. -
A10151 BIX 02189
BIX 02189 is a selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively. -
A10150 BIX02188
BIX02188 is a potent and selective inhibitor of MEK5.
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A11352 CC-401
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
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Product's Reviews
Review by Mayumi Horioka
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works great.
Adooq Bioscience provided high quality compound for my research, with fast delivery and friendly customer service. I had a very positive experience with Adooq.
Adooq Bioscience provided high quality compound for my research, with fast delivery and friendly customer service. I had a very positive experience with Adooq.
Review by Steven Portillo
| Rating: |
Perfect.
We have purchased Atazanavir SL 0101-1 from you and they all worked well. We are very satisfied with its functionality.
We have purchased Atazanavir SL 0101-1 from you and they all worked well. We are very satisfied with its functionality.
Review by Jason
| Rating: |
Excellent service, awesome product!.
A 'strong buy' for my lab experiment! The purity is great, and I got very good results! I am also impressed by their overnight shipping. Will buy some in the future.
A 'strong buy' for my lab experiment! The purity is great, and I got very good results! I am also impressed by their overnight shipping. Will buy some in the future.
Review by Adrew
| Rating: |
Top Quality.
I have tried several AZD6244, this one give me the best results.
I have tried several AZD6244, this one give me the best results.
Review by danise
| Rating: |
Excellent quality.
I used it for my recently experiment, such a good result
I used it for my recently experiment, such a good result
