YM155 (Sepantronium Bromide)

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Survivin Inhibitor

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Catalog No. A11002

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
YM155 5mg A11002-5

Regular Price: $40.00

Special Price: $32.00

YM155 10mg A11002-10

Regular Price: $70.00

Special Price: $56.00

YM155 25mg A11002-25

Regular Price: $150.00

Special Price: $120.00

YM155 100mg A11002-100

Regular Price: $400.00

Special Price: $320.00

YM155 10mM * 1mL in DMSO A11002-10mM-D

Regular Price: $50.00

Special Price: $40.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

YM155 (Sepantronium Bromide)

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Chemical Information

Catalog Num A11002
Actions Inhibitor
M. Wt 443.3
Formula C20H19BrN4O3
Solubility DMSO>89mg/mL Water>89mg/mL Ethanol>24mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 781661-94-7
Synonyms N/A
SMILES code CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
Chemical Name 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide

Biological Activity

Description
YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
Targets
Survivin (HeLa-SURP-luc, CHO-SV40-luc cells)
0.54 nM

Solubility

Solubility (25°C) * In vitro DMSO 55 mg/mL (124.07 mM)
Water 89 mg/mL (200.77 mM)
Ethanol 6 mg/mL (13.53 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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