Baricitinib (LY3009104)

Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).
Grouped product items
Product Name Price Stock Qty
Baricitinib 5mg
$60.00
In stock
Baricitinib 10mg
$70.00
In stock
Baricitinib 25mg
$90.00
In stock
Baricitinib 50mg
$120.00
In stock
Baricitinib (LY3009104) 10mM * 1mL in DMSO
$60.00
In stock
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Adooq Products cited in reputable paper
Adooq's Baricitinib (LY3009104) has been cited by 3 publications
  • Dandan Wang, .et al. , Adv Rheumatol, 2023, May 16;63(1):22 PMID: 37194022
  • Yuki Sasaki, .et al. , JCI Insight, 2022, Apr 8;7(7) PMID: 35393946
  • Yutian Lei, .et al. , Kidney Int, 2021, Feb 16 PMID: 33607177
  • Biological Activity
    Discription Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A11329
    Formula C16H17N7O2S
    Molecular Weight 371.4
    CAS Number 1187594-09-7
    SMILES CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
    Synonyms INCB28050, LY3009104
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 65 mg/mL (175 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.93 mL 134.63 mL 269.25 mL
    0.5 mM 5.39 mL 26.93 mL 53.85 mL
    1 mM 2.69 mL 13.46 mL 26.93 mL
    5 mM 0.54 mL 2.69 mL 5.39 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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