Cyclosporin A

Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.
Grouped product items
Product Name Price Stock Qty
Cyclosporine 25mg
$30.00
In stock
Cyclosporine 100mg
$55.00
In stock
Cyclosporine 200mg
$75.00
In stock
Cyclosporin A 10mM * 1mL in DMSO
$73.00
In stock
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Important Notice: For research use only. We do not sell to patients.

Prop65 Warning  WARNING: Attention California Residents: This product can expose you to chemicals including Cyclosporin A , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Adooq Products cited in reputable paper
Adooq's Cyclosporin A has been cited by 3 publications
  • X Jia, .et al. , J Hazard Mater, 2020, Jun 4;399:123034 PMID: 32544768
  • Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
  • Biological Activity
    Discription Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.
    Targets
    Target Value
    Product Information
    Catalog Num A10260
    Formula C62H111N11O12
    Molecular Weight 1202.6
    CAS Number 59865-13-3
    SMILES CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
    Synonyms Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 99 mg/mL (82.32 mM)
    Water Insoluble
    Ethanol Warmed: 99 mg/mL (82.32 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 8.32 mL 41.58 mL 83.15 mL
    0.5 mM 1.66 mL 8.32 mL 16.63 mL
    1 mM 0.83 mL 4.16 mL 8.32 mL
    5 mM 0.17 mL 0.83 mL 1.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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