Domperidone

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Catalog No. A10329

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Domperidone 100mg A10329-100

Regular Price: $60.00

Special Price: $51.00

Domperidone 500mg A10329-500

Regular Price: $200.00

Special Price: $170.00

Domperidone 10mM * 1mL in DMSO A10329-10mM-D

Regular Price: $62.00

Special Price: $52.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).

Domperidone

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Chemical Information

Catalog Num A10329
Actions N/A
M. Wt 425.91
Formula C22H24ClN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 57808-66-9
Synonyms N/A
SMILES code C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
Chemical Name 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine

Biological Activity

Description
Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).
Targets
Dopamine D2 receptor

Solubility

Solubility (25°C)* In vitro DMSO 48 mg/mL (112.69 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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