GNE-7915

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LRRK2 inhibitor

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Catalog No. A13748

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GNE-7915 10mg A13748-10

Regular Price: $90.00

Special Price: $72.00

GNE-7915 25mg A13748-25

Regular Price: $180.00

Special Price: $144.00

GNE-7915 50mg A13748-50

Regular Price: $300.00

Special Price: $240.00

GNE-7915 100mg A13748-100

Regular Price: $470.00

Special Price: $376.00

GNE-7915 10mM * 1mL in DMSO A13748-10mM-D

Regular Price: $100.00

Special Price: $80.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).

GNE-7915

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Chemical Information

Catalog Num A13748
Actions Inhibitor
M. Wt ?443.39535
Formula C19H21F4N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1351761-44-8
Synonyms GNE7915, GMS 7915
SMILES code CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC
Chemical Name (4-((4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-fluoro-5-methoxyphenyl)(morpholino)methanone

Biological Activity

Description
GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).
Targets
LRRK2 LRRK2
1 nM(Ki)9 nM

Solubility

Solubility (25°C)* In vitro DMSO 22 mg/mL heating (49.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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