LGX 818 (Encorafenib)

Catalog No.: A13226
Selective B-RAF Inhibitor
LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
LGX 818 5mg
$90.00
In stock
LGX 818 10mg
$120.00
In stock
LGX 818 25mg
$190.00
In stock
LGX 818 1mg
$50.00
In stock
LGX 818 10mM * 1mL in DMSO
$110.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's LGX 818 (Encorafenib) has been cited by 1 publications
  • Seidel D, .et al. , Biosens Bioelectron, 2019, Jan 1;123:185-194 PMID: 30201332
  • Biological Activity
    Discription LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A13226
    Formula C22H27ClFN7O4S
    Molecular Weight 540.01
    CAS Number 1269440-17-6, 1269440-29-0
    SMILES C[C@@H](CNC1=NC=CC(=N1)C2=CN(N=C2C3=CC(=CC(=C3F)NS(=O)(=O)C)Cl)C(C)C)NC(=O)OC
    Synonyms LGX818, LGX-818
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 93 mg/mL (172.22 mM)
    Water Insoluble
    Ethanol 93 mg/mL (172.22 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.52 mL 92.59 mL 185.18 mL
    0.5 mM 3.7 mL 18.52 mL 37.04 mL
    1 mM 1.85 mL 9.26 mL 18.52 mL
    5 mM 0.37 mL 1.85 mL 3.7 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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