LY2109761

Catalog No.: A11133
TβRI/II kinase inhibitor
LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
Grouped product items
Product Name Price Stock Qty
LY2109761 5mg
$72.00
In stock
LY2109761 10mg
$122.00
In stock
LY2109761 50mg
$360.00
In stock
LY2109761 100mg
$1,224.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's LY2109761 has been cited by 2 publications
  • Uto T, .et al. , J Allergy Clin Immunol, 2018, Jun;141(6):2156-2167.e9 PMID: 29477579
  • Jared M. Fischer, .et al. , Proc Natl Acad Sci U S A, 2016, Oct 25; 113(43): 12192-12197 PMID: 27791005
  • Biological Activity
    Discription LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
    Product Information
    Catalog Num A11133
    Formula C26H27N5O2
    Molecular Weight 441.5
    CAS Number 700874-71-1
    SMILES C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
    Synonyms LY-2109761
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 2 mg/mL (4.52 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% CMC+0.25% Tween 80 (suspensions) 15 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.65 mL 113.25 mL 226.5 mL
    0.5 mM 4.53 mL 22.65 mL 45.3 mL
    1 mM 2.27 mL 11.33 mL 22.65 mL
    5 mM 0.45 mL 2.27 mL 4.53 mL
    Useful Calculator

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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