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|Storage||at -20°C 3 years Powder|
|Synonyms||ONX0914, ONX 0914, PR-957|
|SMILES code||C[[email protected]@H](C(=O)N[[email protected]@H](CC1=CC=C(C=C1)OC)C(=O)N[[email protected]@H](CC2=CC=CC=C2)C(=O)[[email protected]]3(CO3)C)NC(=O)CN4CCOCC4|
|ONX 0914 is an immunoproteasome inhibitor with potential treatment applications in autoimmune disorders, such as rheumatoid arthritis, inflammatory bowel disease and lupus. ONX 0914 was designed to be a potent inhibitor of the immunoproteasome with minimal cross-reactivity for the constitutive proteasome.|
|Solubility (25°C)*||In vitro||DMSO||100 mg/mL (172.21 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||100 mg/mL (172.21 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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