SC-514
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SC-514 is an orally active, ATP-competitive IKKβ inhibitor (IC50 = 3 - 12 μM) that displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK. | ||
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Targets |
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Catalog Num | A12746 |
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Formula | C9H8N2OS2 |
Molecular Weight | 224.3 |
CAS Number | 354812-17-2 |
SMILES | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N |
Synonyms | SC514, SC 514 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 41 mg/mL (182.79 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 3 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 44.58 mL | 222.92 mL | 445.83 mL |
0.5 mM | 8.92 mL | 44.58 mL | 89.17 mL |
1 mM | 4.46 mL | 22.29 mL | 44.58 mL |
5 mM | 0.89 mL | 4.46 mL | 8.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2