Staurosporine ON SALE PKC inhibitor

158 Customer Reviews
Catalog No. A10864

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Staurosporine 5mg A10864-5

Regular Price: $110.00

Special Price: $93.50

Staurosporine 10mg A10864-10

Regular Price: $150.00

Special Price: $127.50

Staurosporine 25mg A10864-25

Regular Price: $380.00

Special Price: $323.00

Staurosporine 50mg A10864-50

Regular Price: $620.00

Special Price: $527.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. This is achieved through the stronger affinity of staurosporine to the ATP-binding site on the kinase.

Staurosporine

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A10864
Actions Inhibitor
M. Wt 466.5
Formula C28H26N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 62996-74-1
Synonyms AM-2282, STS
SMILES code C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
Chemical Name (9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-m]pyrrolo[3,4-j][1,7]benzodiazonin-1-one

Biological Activity

Description
Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. This is achieved through the stronger affinity of staurosporine to the ATP-binding site on the kinase.
Targets
Target Value
PKCαIC50: 2nM
c-FgrIC50: 2nM
phosphorylasekinaseIC50: 3nM
PKCηIC50: 4nM
PKCγIC50: 5nM
S6kinaseIC50: 5nM
v-SrcIC50: 6nM
Cdc2IC50: 9nM
Cdc2IC50: 9nM
PKAIC50: 15nM
SykIC50: 16nM
PKGIC50: 18nM
PKCδIC50: 20nM
CaMKIIIC50: 20nM
LynIC50: 20nM
MLCKIC50: 21nM
PKCεIC50: 73nM
PKCζIC50: 1086nM

Solubility

Solubility (25°C)* In vitro DMSO 4 mg/mL (8.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.


Keywords:buy Staurosporine | Staurosporine Supplier | purchase Staurosporine | Staurosporine cost | Staurosporine manufacturer | order Staurosporine | Staurosporine distributor | buy 62996-74-1| 62996-74-1 Supplier | purchase 62996-74-1 | 62996-74-1 cost | 62996-74-1 manufacturer | order 62996-74-1 | 62996-74-1 distributor