Vortioxetine (Lu AA21004) hydrobromide

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5-HT Receptor modulator

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Catalog No. A12602

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Vortioxetine (Lu AA21004) hydrobromide 5mg A12602-5

Regular Price: $80.00

Special Price: $64.00

Vortioxetine (Lu AA21004) hydrobromide 10mg A12602-10

Regular Price: $140.00

Special Price: $112.00

Vortioxetine (Lu AA21004) hydrobromide 25mg A12602-25

Regular Price: $280.00

Special Price: $224.00

Vortioxetine (Lu AA21004) hydrobromide 50mg A12602-50

Regular Price: $480.00

Special Price: $384.00

Vortioxetine hydrobromide 10mM * 1mL in DMSO A12602-10mM-D

Regular Price: $120.00

Special Price: $96.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Vortioxetine (Lu AA21004) hydrobromide

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Chemical Information

Catalog Num A12602
Actions Modulator
M. Wt 379.36
Formula C18H22N2S.HBr
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 960203-27-4
Synonyms Lu AA21004, LuAA21004, Lu-AA21004
SMILES code CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C.Br
Chemical Name Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-, hydrobromide (1:1)

Biological Activity

Description
Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
Targets
SERT 5-HT3A 5-HT1A 5-HT7 5-HT1B
1.6 nM(Ki)3.7 nM(Ki)15 nM(Ki)19 nM(Ki)33 nM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 76 mg/mL (200.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 17 mg/mL (44.81 mM)
In vivo 15% Captisol, pH 9 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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