High Purity Kinase Inhibitors on Signaling Pathways

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  • Linagliptin (BI-1356)

    A11224

    Linagliptin (BI-1356)


    Starting at: $150.00

    Linagliptin is a DPP-4 inhibitor, an enzyme that degrades the incretin hormones ...
  • SYN-115

    A11560

    SYN-115


    Starting at: $150.00

    SYN115 is an orally administered, potent and selective inhibitor of the adenosin ...
  • LX 1606

    A11785

    LX 1606


    Starting at: $150.00

    LX 1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) ...
  • CPI-613

    A11786

    CPI-613


    Starting at: $90.00

    CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lip ...
  • GSK2636771

    A11784

    GSK2636771


    Starting at: $150.00

    GSK2636771 is a potent, orally bioavailable, PI3K beta-selective inhibitor. ...
  • BYL719

    A11328

    BYL719


    Starting at: $280.00

    BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor ...
  • AR-C155858

    A11293

    AR-C155858


    Starting at: $350.00

    AR-C155858 is a potent inhibitor of monocarboxylat ...
  • ASP3026

    A11773

    ASP3026


    Starting at: $280.00

    ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently ...

Recommended Products>>See More
  • Everolimus (RAD001)

    A10374Everolimus (RAD001)

    Everolimus (RAD-001) is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an mTOR inhibitor.
  • MLN4924

    A11260MLN4924

    NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.
  • WP1130

    A10988WP1130

    WP1130 is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells.
  • Daptomycin

    A10289Daptomycin

    Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.
  • CHIR-99021

    A10199CHIR-99021

    CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
  • Caftaric acid

    A12025Caftaric acid

    Caftaric acid is a non-flavanoid that impacts the color of white wine.
  • Nutlin-3

    A10657Nutlin-3

    MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
  • Apremilast (CC 10004)

    A11289Apremilast (CC 10004)

    Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.
  • PU-H71

    A11130PU-H71

    PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).
  • MPC-3100

    A11131MPC-3100

    MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
  • PF-562271

    A11192PF-562271

    PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
  • PD 0332991 HCl

    A10701PD 0332991 HCl

    PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
  • SL 0101-1

    A11160SL 0101-1

    SL 0101-1 is a selective inhibitor of p90 ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2). It also inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.

  • EX 527

    A10377EX 527

    EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor.
  • IPI-504 (Retaspimycin hydrochloride)

    A11269IPI-504 (Retaspimycin hydrochloride)

    IPI-504 is a novel, water-soluble, potent inhibitor of heat-shock protein 90 (Hsp90).
  • MLN9708

    A10602MLN9708

    MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.