MGCD0103 (Mocetinostat)

HDAC Inhibitor

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Catalog No. A10586

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MGCD0103 5mg A10586-5

Regular Price: $40.00

Special Price: $32.00

MGCD0103 10mg A10586-10

Regular Price: $50.00

Special Price: $40.00

MGCD0103 25mg A10586-25

Regular Price: $70.00

Special Price: $56.00

MGCD0103 50mg A10586-50

Regular Price: $99.00

Special Price: $79.20

MGCD0103 (Mocetinostat) 10mM * 1mL in DMSO A10586-10mM-D

Regular Price: $55.00

Special Price: $44.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.

MGCD0103 (Mocetinostat)

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Chemical Information

Catalog Num A10586
Actions Inhibitor
M. Wt 396.4
Formula C23H20N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 726169-73-9
Synonyms MGCD-0103
SMILES code C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4
Chemical Name N-(2-Aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl] benzamide

Biological Activity

Description
MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
Targets
Target Value
HDAC1IC50: 0.15μM
HDAC2IC50: 0.29μM
HDAC11IC50: 0.59μM
HDAC3IC50: 1.66μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC6IC50: >10μM
HDAC7IC50: >10μM
HDAC8IC50: >10μM

Solubility

Solubility (25°C) * In vitro DMSO 13 mg/mL (32.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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