Regorafenib monohydrate

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Tyrosine kinase inhibitor

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Catalog No. A15218

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Regorafenib monohydrate 50mg A15218-50

Regular Price: $90.00

Special Price: $72.00

Regorafenib monohydrate 100mg A15218-100

Regular Price: $140.00

Special Price: $112.00

Regorafenib monohydrate 200mg A15218-200

Regular Price: $240.00

Special Price: $192.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR??, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

Regorafenib monohydrate

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Chemical Information

Catalog Num A15218
Actions Inhibitor
M. Wt 500.83
Formula C21H17ClF4N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1019206-88-2
Synonyms BAY 73-4506 monohydrate
SMILES code CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
Chemical Name 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate

Biological Activity

Description
Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR??, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

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