VDA

Inhibitory Selectivity
Catalog No.Inhibitor Name VDAOther
A10324DMXAA (ASA404, Vadimezan)
**
A10654NPI-2358 (Plinabulin)
***
A12658Verteporfin
YAP/TEAD interaction

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.



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Catalog No. Product Name Application Product Information
A10324 SALE

DMXAA (ASA404, Vadimezan)

Vascular Disrupting Agent (VDA)
DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
A10654 SALE

NPI-2358 (Plinabulin)

Microtubule Inhibitor
NPI-2358 is a synthetic analog of NPI-2350, a natural product isolated from Aspergillus sp., which depolymerizes microtubules in A549 human lung carcinoma cells.
A12658 SALE

Verteporfin

YAP inhibitor
Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

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