17-AAG (KOS953)

Catalog No.: A10010
HSP90 inhibitor
17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.
Grouped product items
Product Name Price Stock Qty
17-AAG 10mg
$60.00
In stock
17-AAG 100mg
$250.00
In stock
17-AAG 200mg
$350.00
In stock
17-AAG 50mg
$160.00
In stock
17-AAG (KOS953) 10mM * 1mL in DMSO
$82.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's 17-AAG (KOS953) has been cited by 1 publications
  • Yool Lee, .et al. , Sci Adv, 2021, 7
  • Biological Activity
    Discription 17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.
    Targets
    Target Value
    Product Information
    Catalog Num A10010
    Formula C31H43N3O8
    Molecular Weight 585.7
    CAS Number 75747-14-7
    SMILES CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
    Synonyms Tanespimycin, NSC330507, CP 127374
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 97 mg/mL (165.61 mM)
    Water Insoluble
    Ethanol 5 mg/mL
    In vivo 5%DMSO+corn oil 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.07 mL 85.37 mL 170.74 mL
    0.5 mM 3.41 mL 17.07 mL 34.15 mL
    1 mM 1.71 mL 8.54 mL 17.07 mL
    5 mM 0.34 mL 1.71 mL 3.41 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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