17-AAG (KOS953)

Catalog No.: A10010

HSP90 inhibitor

17-AAG (KOS953) Chemical Structure

CAS NO. 75747-14-7

17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.

Availability: In stock

Package Price Qty
10 mg
$40.00
50 mg
$160.00
100 mg
$250.00
200 mg
$350.00
10mM * 1mL in DMSO
$82.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90.
Targets
HSP90 (Cell-free assay)
5 nM
In vitro DMSO 117 mg/mL (199.76 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (8.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.07 mL 85.37 mL 170.74 mL
0.5 mM 3.41 mL 17.07 mL 34.15 mL
1 mM 1.71 mL 8.54 mL 17.07 mL
5 mM 0.34 mL 1.71 mL 3.41 mL

*The above data is based on the productmolecular weight 585.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10010
Actions Inhibitor
M. Wt 585.7
Formula C31H43N3O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75747-14-7
Synonyms Tanespimycin, NSC330507, CP 127374, KOS-953, KOS 953
SMILES CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

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