GPCR/G Protein

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  1. Sirt2 inhibitor

    SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM.
  2. PROTAC BET-binding moiety 1 is a key intermediate for the synthesis of high-affinity BET inhibitors.

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