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A-3 Hydrochloride is an inhibitor of PKA (cAMP-dependent protein kinase, Ki=4.3μM) and cGMP-dependent protein kinase, Ki=3.8μM, PKC (protein kinase C, Ki=47μM), casein kinase I and II, and MLCK (myosin light chain kinase) ( Ki=7.4μM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.13 mL | 155.66 mL | 311.31 mL |
| 0.5 mM | 6.23 mL | 31.13 mL | 62.26 mL |
| 1 mM | 3.11 mL | 15.57 mL | 31.13 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.23 mL |
*The above data is based on the productmolecular weight 321.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13584 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 78957-85-4 |
| Formula | C12H14Cl2N2O2S |
| M. Wt | 321.22 |
| Purity | >98% |
| SMILES | C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCN.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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