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A 967079

Catalog No.: A12353

TRPA1 channel blocker

A 967079

A 967079 Chemical Structure

CAS NO. 1170613-55-4

A 967079 is a selective TRPA1 channel blocker (IC50 values are 67 and 289 nM at human and rat TRPA1 receptors respectively).

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • L Jin, .et al. Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications, Toxicol Appl Pharmacol, 2021, Jul 13;426:115647 PMID: 34271065
  • L. Jin, .et al. Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1), Toxicology and Applied Pharmacology, 2020, 398(1),

Biological Activity

A 967079 is a selective TRPA1 channel blocker (IC50 values are 67 and 289 nM at human and rat TRPA1 receptors respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.25 mL 241.27 mL 482.53 mL
0.5 mM 9.65 mL 48.25 mL 96.51 mL
1 mM 4.83 mL 24.13 mL 48.25 mL
5 mM 0.97 mL 4.83 mL 9.65 mL

*The above data is based on the productmolecular weight 207.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12353
Actions Blocker
CAS No. 1170613-55-4
Formula C12H14FNO
M. Wt 207.24
Purity >98%
Synonyms A-967079, A967079

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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