Signaling Pathway
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| Discription | AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM. | ||
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| Targets |
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| Catalog Num | A11022 |
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| Formula | C16H14ClN3O2 |
| Molecular Weight | 315.8 |
| CAS Number | 153436-53-4 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC |
| Synonyms | AG1478, AG 1478 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 25 mg/mL (79.17 mM) | |
| Water | Insoluble | ||
| Ethanol | 13 mg/mL (41.17 mM) | ||
| In vivo | 15% Captisol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.67 mL | 158.33 mL | 316.66 mL |
| 0.5 mM | 6.33 mL | 31.67 mL | 63.33 mL |
| 1 mM | 3.17 mL | 15.83 mL | 31.67 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.33 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
