AG-1478 (Tyrphostin AG-1478)

AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.
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Product Name Price Stock Qty
AG-1478 5mg
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AG-1478 10mg
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AG-1478 25mg
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AG-1478 50mg
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AG-1478 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's AG-1478 (Tyrphostin AG-1478) has been cited by 2 publications
  • Khattab M, .et al. , J Phys Chem B, 2018, May 3;122(17):4667-4679 PMID: 29629773
  • Muhammad Khattab, .et al. , Sci Rep, 2017, 7: 16271 PMID: 29176733
  • Biological Activity
    Discription AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.
    Target Value
    Product Information
    Catalog Num A11022
    Formula C16H14ClN3O2
    Molecular Weight 315.8
    CAS Number 153436-53-4
    SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
    Synonyms AG1478, AG 1478

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 25 mg/mL (79.17 mM)
    Water Insoluble
    Ethanol 13 mg/mL (41.17 mM)
    In vivo 15% Captisol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.67 mL 158.33 mL 316.66 mL
    0.5 mM 6.33 mL 31.67 mL 63.33 mL
    1 mM 3.17 mL 15.83 mL 31.67 mL
    5 mM 0.63 mL 3.17 mL 6.33 mL
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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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