AGI-6780

Catalog No.: A12903

IDH2 R140Q inhibitor

AGI-6780

AGI-6780 Chemical Structure

CAS NO. 1432660-47-3

AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $64.00

10 mg

Regular Price: $140.00

Special Price $112.00

25 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO
$136.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.
Targets
IDH2 R140Q mutant
23 nM
In vitro DMSO 96 mg/mL (199.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 96 mg/mL (199.37 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.84 mL 207.68 mL
0.5 mM 4.15 mL 20.77 mL 41.54 mL
1 mM 2.08 mL 10.38 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12903
Actions Inhibitor
M. Wt 481.5
Formula C21H18F3N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1432660-47-3
Synonyms AGI6780
SMILES C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F

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