Catalog No.: A12903
IDH2 R140Q inhibitor
AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.
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AGI-6780 5mg
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AGI-6780 10mg
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AGI-6780 25mg
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AGI-6780 50mg
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AGI-6780 10mM * 1mL in DMSO
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Biological Activity
Discription AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.
Target Value
Product Information
Catalog Num A12903
Formula C21H18F3N3O3S
Molecular Weight 481.5
CAS Number 1432660-47-3
Synonyms AGI6780

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 87 mg/mL (180.68 mM)
Water Insoluble
Ethanol 87 mg/mL (180.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.84 mL 207.68 mL
0.5 mM 4.15 mL 20.77 mL 41.54 mL
1 mM 2.08 mL 10.38 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL
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