AHU-377 (Sacubitril calcium)

Catalog No.: A13682

neprilysin inhibitor

AHU-377 (Sacubitril calcium)

AHU-377 (Sacubitril calcium) Chemical Structure

CAS NO. 149709-62-6

AHU-377 is an inhibitor of neprilysin with IC50 value of 5nM.

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Biological Activity

AHU-377 is an inhibitor of neprilysin with IC50 value of 5nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.3 mL 121.51 mL 243.02 mL
0.5 mM 4.86 mL 24.3 mL 48.6 mL
1 mM 2.43 mL 12.15 mL 24.3 mL
5 mM 0.49 mL 2.43 mL 4.86 mL

*The above data is based on the productmolecular weight 411.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13682
Actions Inhibitor
CAS No. 149709-62-6
Formula C24H29NO5
M. Wt 411.49
Purity >98%
Synonyms AHU377, AHU 377, Sacubitril
SMILES CCOC(=O)[[email protected]](C)C[[email protected]@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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