AMG 208

Catalog No.: A10063

c-Met Inhibitor

AMG 208

AMG 208 Chemical Structure

CAS NO. 1002304-34-8

AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
50 mg
$550.00
100 mg
$750.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity.
Targets
c-Met
9 nM
In vitro (25°C) DMSO 0.25 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.08 mL 130.41 mL 260.82 mL
0.5 mM 5.22 mL 26.08 mL 52.16 mL
1 mM 2.61 mL 13.04 mL 26.08 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10063
Actions Inhibitor
M. Wt 383.4
Formula C22H17N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1002304-34-8
Synonyms AMG208, AMG-208
SMILES COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy AMG 208 | AMG 208 Supplier | purchase AMG 208 | AMG 208 cost | AMG 208 manufacturer | order AMG 208 | AMG 208 distributor | buy 1002304-34-8 | 1002304-34-8 Supplier | purchase 1002304-34-8 | 1002304-34-8 cost | 1002304-34-8 manufacturer | order 1002304-34-8 | 1002304-34-8 distributor
Rewards