AMG 837

Catalog No.: A21160

GPR40 agonist

AMG 837

AMG 837 Chemical Structure

CAS NO. 865231-46-5

AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$242.00
50 mg
$718.00
100 mg
$1,435.00
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Biological Activity

AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.04 mL 228.08 mL
0.5 mM 4.56 mL 22.81 mL 45.62 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21160
Actions Agonist
M. Wt 438.44
Formula C26H21F3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 865231-46-5
SMILES OC(C[[email protected]](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O

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