AMG-925

Catalog No.: A14025

Dual FLT3/CDK4 inhibitor

AMG-925 Chemical Structure

CAS NO. 1401033-86-0

AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $150.00

Special Price $120.00

25 mg

Regular Price: $250.00

Special Price $200.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.
Targets
FLT3 CDK4 CDK1
1 nM3 nM2.22 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.03 mL 212.07 mL
0.5 mM 4.24 mL 21.21 mL 42.41 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14025
Actions Inhibitor
M. Wt 471.55
Formula C26H29N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1401033-86-0
Synonyms AMG925, AMG 925
SMILES CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5

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