AMG517

Catalog No.: A12727
TRPV1 antagonist
AMG 517 is a potent and selective TRPV1 antagonist.
Grouped product items
Product Name Price Stock Qty
AMG517 5mg
$50.00
In stock
AMG517 10mg
$90.00
In stock
AMG517 25mg
$200.00
In stock
AMG517 50mg
$380.00
In stock
AMG517 10mM * 1mL in DMSO
$136.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AMG517 has been cited by 2 publications
  • Jun Hai, .et al. , Biosci Biotechnol Biochem, 2020, Jul 7;1-7 PMID: 32633621
  • Hai J, .et al. , Biomed Res, 2018, 39(6):279-286 PMID: 30531157
  • Biological Activity
    Discription AMG 517 is a potent and selective TRPV1 antagonist.
    Targets
    Target Value
    Product Information
    Catalog Num A12727
    Formula C20H13F3N4O2S
    Molecular Weight 430.4
    CAS Number 659730-32-2
    SMILES CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F
    Synonyms AMG 517, AMG-517
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 84 mg/mL (195.16 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 10% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.23 mL 116.17 mL 232.34 mL
    0.5 mM 4.65 mL 23.23 mL 46.47 mL
    1 mM 2.32 mL 11.62 mL 23.23 mL
    5 mM 0.46 mL 2.32 mL 4.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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