Ampalex (CX-516)

Catalog No.: A12349

Ampalex (CX-516)

Ampalex (CX-516) Chemical Structure

CAS NO. 154235-83-3

Ampalex is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator

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  • Mariusz Papp, .et al. AMPA receptors mediate the pro-cognitive effects of electrical and optogenetic stimulation of the medial prefrontal cortex in antidepressant non-responsive Wistar-Kyoto rats, J Psychopharmacol, 2020, Dec;34(12):1418-1430 PMID: 33200659
  • Abigail Benn, .et al. Optogenetic Stimulation of Prefrontal Glutamatergic Neurons Enhances Recognition Memory, J Neurosci, 2016, May 4; 36(18):4930-4939 PMID: 27147648
  • >

Biological Activity

Ampalex is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator
In vitro DMSO 41 mg/mL (169.92 mM)
Water 41 mg/mL (169.92 mM)
Ethanol 41 mg/mL (169.92 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.44 mL 207.22 mL 414.44 mL
0.5 mM 8.29 mL 41.44 mL 82.89 mL
1 mM 4.14 mL 20.72 mL 41.44 mL
5 mM 0.83 mL 4.14 mL 8.29 mL

*The above data is based on the productmolecular weight 241.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12349
CAS No. 154235-83-3
Formula C14H15N3O
M. Wt 241.29
Purity >98%
Synonyms CX516, CX 516

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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