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Anisomycin

Catalog No.: A11271

SAPKs/JNKs activator

Anisomycin

Anisomycin Chemical Structure

CAS NO. 22862-76-6

Anisomycin is a pyrrolidine antibiotic, acts as an anti-fungal antibiotic which inhibits Protein Synthesis, also is a potent activator of SAPKs/JNKs.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$80.00
100 mg
$150.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Ken Kobayashi, .et al. Lactose on the basolateral side of mammary epithelial cells inhibits milk production concomitantly with signal transducer and activator of transcription 5 inactivation, Cell Tissue Res, 2022, Sep;389(3):501-515 PMID: 35748981
  • Li Li, .et al. The mutual regulatory loop between TPTEP1 and miR-1303 in leukemogenesis of acute myeloid leukemia, Cancer Cell Int, 2021, May 13;21(1):260 PMID: 33985519

Biological Activity

Anisomycin is a pyrrolidine antibiotic, acts as an anti-fungal antibiotic which inhibits Protein Synthesis, also is a potent activator of SAPKs/JNKs.
Targets
JNK
In vitro (25°C) DMSO Warmed: 35 mg/mL (131.92 mM)
Water Insoluble
Ethanol Warmed: 14 mg/mL (52.76 mM)
In vivo 2% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.69 mL 188.46 mL 376.92 mL
0.5 mM 7.54 mL 37.69 mL 75.38 mL
1 mM 3.77 mL 18.85 mL 37.69 mL
5 mM 0.75 mL 3.77 mL 7.54 mL

*The above data is based on the productmolecular weight 265.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11271
Actions Activator
CAS No. 22862-76-6
Formula C14H19NO4
M. Wt 265.31
Purity >98%
Synonyms Flagecidin, Wuningmeisu C
SMILES O[C@@H]1[C@H]([C@@H](CC(C=C2)=CC=C2OC)NC1)OC(C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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