AST-1306

Catalog No.: A11155

EGFR Inhibitor

AST-1306

AST-1306 Chemical Structure

CAS NO. 897383-62-9

AST-1306, a novel anilino-quinazoline compound, inhibits the enzymatic activities of wild-type epidermal growth factor receptor (EGFR) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $800.00

Special Price $640.00

100 mg

Regular Price: $1,400.00

Special Price $1,120.00

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Biological Activity

AST-1306, a novel anilino-quinazoline compound, inhibits the enzymatic activities of wild-type epidermal growth factor receptor (EGFR) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.28 mL 111.38 mL 222.77 mL
0.5 mM 4.46 mL 22.28 mL 44.55 mL
1 mM 2.23 mL 11.14 mL 22.28 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11155
Actions Inhibitor
CAS No. 897383-62-9
Formula C24H18ClFN4O2
M. Wt 448.9
Purity >98%
Synonyms AST1306
SMILES C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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