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Biological Activity
AZ 10417808, selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 uM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.03 mL | 115.15 mL | 230.29 mL |
| 0.5 mM | 4.61 mL | 23.03 mL | 46.06 mL |
| 1 mM | 2.3 mL | 11.51 mL | 23.03 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.61 mL |
*The above data is based on the productmolecular weight 434.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15294 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 331645-84-2 |
| Formula | C18H13Cl2N5O4 |
| M. Wt | 434.23 |
| Purity | >98% |
| SMILES | C=CCNC(=O)C1=C2C(=CC(=C1)[N+](=O)[O-])C(=O)N=C(N2)NC3=CC(=C(C=C3)Cl)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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