AZ-960

Catalog No.: A10104

JAK2inhibitor

AZ-960

AZ-960 Chemical Structure

CAS NO. 905586-69-8

AZ-960 is a potent, selective and ATP competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $200.00

Special Price $180.00

10 mg

Regular Price: $320.00

Special Price $288.00

25 mg

Regular Price: $550.00

Special Price $495.00

50 mg

Regular Price: $920.00

Special Price $828.00

10mM * 1mL in DMSO

Regular Price: $201.00

Special Price $180.90

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZ-960 is a potent, selective and ATP competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell.
Targets
JAK2 JAK2
0.45 nM(Ki)<3 nM
In vitro DMSO 71 mg/mL (200.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (8.46 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.22 mL 141.08 mL 282.17 mL
0.5 mM 5.64 mL 28.22 mL 56.43 mL
1 mM 2.82 mL 14.11 mL 28.22 mL
5 mM 0.56 mL 2.82 mL 5.64 mL

*The above data is based on the productmolecular weight 354.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10104
Actions Inhibitor
M. Wt 354.4
Formula C18H16F2N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 905586-69-8
Synonyms AZ960
SMILES CC1=CC(=NN1)NC2=C(C=C(C(=N2)N[[email protected]@H](C)C3=CC=C(C=C3)F)C#N)F

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