AZ-960

Catalog No.: A10104
JAK2inhibitor
AZ-960 is a potent, selective and ATP competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell.
Grouped product items
Product Name Price Stock Qty
AZ-960 5mg
Special Price $160.00 Regular Price $200.00
In stock
AZ-960 10mg
Special Price $256.00 Regular Price $320.00
In stock
AZ-960 25mg
Special Price $440.00 Regular Price $550.00
In stock
AZ-960 50mg
Special Price $736.00 Regular Price $920.00
In stock
AZ-960 10mM * 1mL in DMSO
Special Price $160.80 Regular Price $201.00
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Biological Activity
Discription AZ-960 is a potent, selective and ATP competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell.
Targets
Target Value
Product Information
Catalog Num A10104
Formula C18H16F2N6
Molecular Weight 354.4
CAS Number 905586-69-8
SMILES CC1=CC(=NN1)NC2=C(C=C(C(=N2)N[C@@H](C)C3=CC=C(C=C3)F)C#N)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 70 mg/mL (197.54 mM)
Water Insoluble
Ethanol 3 mg/mL (8.46 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.22 mL 141.08 mL 282.17 mL
0.5 mM 5.64 mL 28.22 mL 56.43 mL
1 mM 2.82 mL 14.11 mL 28.22 mL
5 mM 0.56 mL 2.82 mL 5.64 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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