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JAK Inhibitor

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Catalog No. A10110

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD1480 5mg A10110-5

Regular Price: $50.00

Special Price: $45.00

AZD1480 10mg A10110-10

Regular Price: $80.00

Special Price: $72.00

AZD1480 50mg A10110-50

Regular Price: $200.00

Special Price: $180.00

AZD1480 200mg A10110-200

Regular Price: $650.00

Special Price: $585.00

AZD1480 10mM * 1mL in DMSO A10110-10mM-D

Regular Price: $94.00

Special Price: $84.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.


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Chemical Information

Catalog Num A10110
Actions Inhibitor
M. Wt 348.8
Formula C14H14ClFN8
Solubility DMSO>70mg/mL Water<1mg/mL Ethanol>5mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 935666-88-9
Synonyms N/A
SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[[email protected]@H](C)C3=NC=C(C=N3)F

Biological Activity

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.
JAK2 (Cell-free assay)
0.26 nM


Solubility (25°C) * In vitro DMSO 69 mg/mL heating (197.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.67 mL 143.35 mL 286.7mL
0.5 mM 5.73 mL 28.67 mL 57.34 mL
1 mM 2.87 mL 14.33 mL 28.67 mL
5 mM 0.57 mL 2.87 mL 5.73 mL

*The above data is based on the productmolecular weight 348.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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