AZD1480

Catalog No.: A10110

JAK Inhibitor

AZD1480

AZD1480 Chemical Structure

CAS NO. 935666-88-9

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $50.00

Special Price $45.00

10 mg

Regular Price: $80.00

Special Price $72.00

50 mg

Regular Price: $200.00

Special Price $180.00

200 mg

Regular Price: $650.00

Special Price $585.00

10mM * 1mL in DMSO

Regular Price: $94.00

Special Price $84.60

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.
Targets
JAK2 (Cell-free assay)
0.26 nM
In vitro (25°C) DMSO 69 mg/mL heating (197.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.67 mL 143.35 mL 286.7 mL
0.5 mM 5.73 mL 28.67 mL 57.34 mL
1 mM 2.87 mL 14.33 mL 28.67 mL
5 mM 0.57 mL 2.87 mL 5.73 mL

*The above data is based on the productmolecular weight 348.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10110
Actions Inhibitor
M. Wt 348.8
Formula C14H14ClFN8
Solubility DMSO>70mg/mL Water<1mg/mL Ethanol>5mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 935666-88-9
Synonyms N/A
SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[[email protected]@H](C)C3=NC=C(C=N3)F

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