AZD1480
AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.
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Adooq Products cited in reputable paper
Adooq's AZD1480 has been cited by 1 publications
Biological Activity
| Discription | AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM. | |||||
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| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A10110 |
|---|---|
| Formula | C14H14ClFN8 |
| Molecular Weight | 348.8 |
| CAS Number | 935666-88-9 |
| SMILES | CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[C@@H](C)C3=NC=C(C=N3)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | Warmed: 68 mg/mL (194.96 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.67 mL | 143.35 mL | 286.7 mL |
| 0.5 mM | 5.73 mL | 28.67 mL | 57.34 mL |
| 1 mM | 2.87 mL | 14.33 mL | 28.67 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.73 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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