Catalog No.: A10110

JAK Inhibitor


AZD1480 Chemical Structure

CAS NO. 935666-88-9

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.

Availability: In stock

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5 mg
10 mg
50 mg
200 mg
10mM * 1mL in DMSO
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Biological Activity

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.
JAK2 (Cell-free assay)
0.26 nM
In vitro (25°C) DMSO Warmed: 68 mg/mL (194.96 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.67 mL 143.35 mL 286.7 mL
0.5 mM 5.73 mL 28.67 mL 57.34 mL
1 mM 2.87 mL 14.33 mL 28.67 mL
5 mM 0.57 mL 2.87 mL 5.73 mL

*The above data is based on the productmolecular weight 348.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10110
Actions Inhibitor
CAS No. 935666-88-9
Formula C14H14ClFN8
M. Wt 348.8
Purity >98%
SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[[email protected]@H](C)C3=NC=C(C=N3)F

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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