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Biological Activity
AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM.
Targets
| CRTh2 (DP2) receptor | ||||
| 4 nM |
| In vitro | DMSO | 9 mg/mL (23.14 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.72 mL | 128.58 mL | 257.16 mL |
| 0.5 mM | 5.14 mL | 25.72 mL | 51.43 mL |
| 1 mM | 2.57 mL | 12.86 mL | 25.72 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
*The above data is based on the productmolecular weight 388.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13186 |
|---|---|
| Actions | Antagonist |
| CAS No. | 802904-66-1 |
| Formula | C19H17ClN2O3S |
| M. Wt | 388.87 |
| Purity | >98% |
| Synonyms | AZD-1981, AZD 1981 |
| SMILES | CC1=C(C2=C(N1CC(=O)O)C=CC=C2NC(=O)C)SC3=CC=C(C=C3)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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