β3-AR agonist 1

Catalog No.: A12777

β3-adrenergic receptor agonist

β3-AR agonist 1

β3-AR agonist 1 Chemical Structure

CAS NO. 1283125-73-4

β3-AR agonist 1 (compound 15) is a highly potent, selective, and orally available β3-adrenergic receptor (β3-AR) agonist (EC50=18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

β3-AR agonist 1 (compound 15) is a highly potent, selective, and orally available β3-adrenergic receptor (β3-AR) agonist (EC50=18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.49 mL 112.47 mL 224.95 mL
0.5 mM 4.5 mL 22.49 mL 44.99 mL
1 mM 2.25 mL 11.25 mL 22.49 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12777
Actions Agonist
M. Wt 444.55
Formula C22H28N4O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1283125-73-4
SMILES O=S(NC1=CC([[email protected]@H](O)CNCCOC2=CC(NN=C3C)=C3C=C2)=CC=C1)(C4CCC4)=O

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