BMS-708163 (Avagacestat)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | BMS-708163 is an oral gamma secretase inhibitor designed for selective inhibition of amyloid beta synthesis. | ||
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Targets |
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Catalog Num | A10157 |
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Formula | C20H17ClF4N4O4S |
Molecular Weight | 520.8 |
CAS Number | 1146699-66-2 |
SMILES | C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)[C@H](CCC(F)(F)F)C(=O)N)Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (172.78 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.2 mL | 96.01 mL | 192.01 mL |
0.5 mM | 3.84 mL | 19.2 mL | 38.4 mL |
1 mM | 1.92 mL | 9.6 mL | 19.2 mL |
5 mM | 0.38 mL | 1.92 mL | 3.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2