BMS-833923 (XL-139)

Catalog No.: A13204

Smoothened inhibitor

BMS-833923 (XL-139)

BMS-833923 (XL-139) Chemical Structure

CAS NO. 1059734-66-5

BMS-833923 (or XL-139) is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$70.00
25 mg
$140.00
50 mg
$200.00
10mM * 1mL in DMSO
$100.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Valérian Pasche, .et al. Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni, Parasit Vectors, 2018, 11: 298 PMID: 29764454

Biological Activity

BMS-833923 (or XL-139) is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity.
Targets
Smoothened
In vitro DMSO 95 mg/mL (200.6 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.12 mL 105.58 mL 211.16 mL
0.5 mM 4.22 mL 21.12 mL 42.23 mL
1 mM 2.11 mL 10.56 mL 21.12 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 473.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13204
Actions Inhibitor
M. Wt 473.57
Formula C30H27N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1059734-66-5
Synonyms XL139, XL 139, BMS833923, BMS 833923
SMILES CC1=C(C=C(C=C1)CNC)NC(=O)C2=CC=C(C=C2)NC3=NC4=CC=CC=C4C(=N3)C5=CC=CC=C5

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