Total item
Cart Subtotal
$0.00 Biological Activity
BMS-911543 is an orally available small molecule targeting a subset of Janus-associated kinase (JAK) with potential antineoplastic activity.
Targets
| JAK2 | SET-2 | TYK2 | JAK3 | JAK1 |
| 1.1 nM | 60 nM | 66 nM | 75 nM | 360 nM |
| In vitro | DMSO | 36 mg/mL (83.23 mM) | |
| Water | Insoluble | ||
| Ethanol | 22 mg/mL (50.86 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.12 mL | 115.6 mL | 231.2 mL |
| 0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11241 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1271022-90-2 |
| Formula | C23H28N8O |
| M. Wt | 432.52 |
| Purity | >98% |
| Synonyms | BMS911543, BMS 911543 |
| SMILES | CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
INCB018424 (Ruxolitinib)
INCB018424 is a potent and selective inhibitor of Janus-associated kinase (JAK) 1 and 2, with IC50 to be 2.7, 4.5 and 332 nM for JAK1, JAK2 …
WHI-P 154
WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages…
Cyt387 (Momelotinib)
CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.
FLLL32
FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of
PP2
PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays…
AG-490
AG 490 is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Also inhib…
ZM 39923 HCl
ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent…
Go 6976
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent…
Keywords:buy BMS-911543 | BMS-911543 Supplier | purchase | cost | manufacturer | order | distributor | buy 1271022-90-2| 1271022-90-2 Supplier | purchase 1271022-90-2 | 1271022-90-2 cost | 1271022-90-2 manufacturer | order 1271022-90-2 | 1271022-90-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.