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PI3K inhibitor

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Catalog No. A11196

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CAY10505 10mg A11196-10

Regular Price: $40.00

Special Price: $36.00

CAY10505 25mg A11196-25

Regular Price: $80.00

Special Price: $72.00

CAY10505 50mg A11196-50

Regular Price: $140.00

Special Price: $126.00

CAY10505 200mg A11196-200

Regular Price: $400.00

Special Price: $360.00

CAY10505 10mM * 1mL in DMSO A11196-10mM-D

Regular Price: $71.00

Special Price: $63.90

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively).


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Chemical Information

Catalog Num A11196
Actions Inhibitor
M. Wt 289.28
Formula C14H8FNO3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1218777-13-9
Synonyms CAY-10505
SMILES C1=CC(=CC=C1C2=CC=C(O2)/C=C/3\C(=O)NC(=O)S3)F

Biological Activity


CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively).


Solubility (25°C)* In vitro DMSO 58 mg/mL (200.49 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.57 mL 172.84 mL 345.69mL
0.5 mM 6.91 mL 34.57 mL 69.14 mL
1 mM 3.46 mL 17.28 mL 34.57 mL
5 mM 0.69 mL 3.46 mL 6.91 mL

*The above data is based on the productmolecular weight 289.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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