Glucokinase

GKA50 is a potent activator of glucokinase

Piragliatin is a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus

Glucokinase activator 1 is a liver-directed glucokinase activator with an EC50 of 34 nM.