Catalog No.: A11085
GSK-3 inhibitor
CHIR-98014 is a very potent, selective, cell-permeable reversible inhibitor of GSK-3.
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CHIR-98014 5mg
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CHIR-98014 10mg
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CHIR-98014 50mg
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CHIR-98014 100mg
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Biological Activity
Discription CHIR-98014 is a very potent, selective, cell-permeable reversible inhibitor of GSK-3.
Target Value
Product Information
Catalog Num A11085
Formula C20H17Cl2N9O2
Molecular Weight 486.3
CAS Number 252935-94-7
SMILES C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N
Synonyms CHIR98014

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO Warmed: 7 mg/mL (14.39 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.56 mL 102.82 mL 205.63 mL
0.5 mM 4.11 mL 20.56 mL 41.13 mL
1 mM 2.06 mL 10.28 mL 20.56 mL
5 mM 0.41 mL 2.06 mL 4.11 mL
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