SANT-1
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SANT-1 is a potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells). | ||
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Targets |
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Catalog Num | A13095 |
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Formula | C23H27N5 |
Molecular Weight | 373.5 |
CAS Number | 304909-07-7 |
SMILES | CC1=C(C(=NN1C2=CC=CC=C2)C)/C=N/N3CCN(CC3)CC4=CC=CC=C4 |
Synonyms | SANT 1, SANT1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 21 mg/mL (56.22 mM) | |
Water | Insoluble | ||
Ethanol | 20 mg/mL (53.54 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.77 mL | 133.87 mL | 267.74 mL |
0.5 mM | 5.35 mL | 26.77 mL | 53.55 mL |
1 mM | 2.68 mL | 13.39 mL | 26.77 mL |
5 mM | 0.54 mL | 2.68 mL | 5.35 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2