FG-2216
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo, | ||
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Catalog Num | A15530 |
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Formula | C12H9ClN2O4 |
Molecular Weight | 280.66 |
CAS Number | 223387-75-5 |
SMILES | C1=CC=C2C(=C1)C(=C(N=C2Cl)C(=O)NCC(=O)O)O |
Synonyms | YM-311 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 48 mg/mL (171.02 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+40% PEG 300+2% Twenn 80+ddH2O | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.63 mL | 178.15 mL | 356.3 mL |
0.5 mM | 7.13 mL | 35.63 mL | 71.26 mL |
1 mM | 3.56 mL | 17.82 mL | 35.63 mL |
5 mM | 0.71 mL | 3.56 mL | 7.13 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2