MLN8237 (Alisertib)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | MLN8237 (Alisertib) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Phase 3.. | ||
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Catalog Num | A10004 |
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Formula | C27H20ClFN4O4 |
Molecular Weight | 518.9 |
CAS Number | 1028486-01-2 |
SMILES | COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 23 mg/mL (44.32 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5%DMSO+30% PEG300+5%Tween-80+ddH2O | 5 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.27 mL | 96.36 mL | 192.72 mL |
0.5 mM | 3.85 mL | 19.27 mL | 38.54 mL |
1 mM | 1.93 mL | 9.64 mL | 19.27 mL |
5 mM | 0.39 mL | 1.93 mL | 3.85 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2