Macitentan
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH). | ||
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Catalog Num | A11492 |
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Formula | C19H20Br2N6O4S |
Molecular Weight | 588.27 |
CAS Number | 441798-33-0 |
SMILES | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br |
Synonyms | ACT 064992, ACT-064992, ACT064992 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 87 mg/mL (147.88 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17 mL | 84.99 mL | 169.99 mL |
0.5 mM | 3.4 mL | 17 mL | 34 mL |
1 mM | 1.7 mL | 8.5 mL | 17 mL |
5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2