XL147 analogue
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity. | ||
---|---|---|---|
Targets |
|
Catalog Num | A10995 |
---|---|
Formula | C21H16N6O2S2 |
Molecular Weight | 448.5 |
CAS Number | 956958-53-5 |
SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4 |
Synonyms | XL-147, SAR245408 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 3 mg/mL (6.68 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.3 mL | 111.48 mL | 222.97 mL |
0.5 mM | 4.46 mL | 22.3 mL | 44.59 mL |
1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2