TH287
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16, | ||
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Targets |
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Catalog Num | A15536 |
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Formula | C11H10Cl2N4 |
Molecular Weight | 269.13 |
CAS Number | 1609960-30-6 |
SMILES | CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N |
Synonyms | TH-287, TH 287 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 48 mg/mL (178.35 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 9 mg/mL (33.44 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 37.16 mL | 185.78 mL | 371.57 mL |
0.5 mM | 7.43 mL | 37.16 mL | 74.31 mL |
1 mM | 3.72 mL | 18.58 mL | 37.16 mL |
5 mM | 0.74 mL | 3.72 mL | 7.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2