GF 109203X
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | GF 109203X is a potent and selective inhibitor of protein kinase C, selective for the α and β1 isoforms (IC50 values are 0.0084, 0.0180, 0.210, 0.132, and 5.8 μM for α, β1, δ, ε and ζ isoforms respectively). Selective over MLCK, PKG and PKA (IC50 values are 0.6, 4.6, and 33 μM respectively). Potent antagonist at the 5-HT3 receptor (Ki = 29.5 nM). | ||
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Targets |
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Catalog Num | A13197 |
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Formula | C25H24N4O2 |
Molecular Weight | 412.49 |
CAS Number | 133052-90-1 |
SMILES | CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
Synonyms | GF-109203X, GF109203X, GO6850, GO-6850, Bisindolylmaleimide I |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 70 mg/mL (169.7 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.24 mL | 121.22 mL | 242.43 mL |
0.5 mM | 4.85 mL | 24.24 mL | 48.49 mL |
1 mM | 2.42 mL | 12.12 mL | 24.24 mL |
5 mM | 0.48 mL | 2.42 mL | 4.85 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2