LY3023414
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242). | ||
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Catalog Num | A16126 |
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Formula | C23H26N4O3 |
Molecular Weight | 406.49 |
CAS Number | 1386874-06-1 |
SMILES | CC(CN1C2=C3C=C(C=CC3=NC=C2N(C1=O)C)C4=CC(=CN=C4)C(C)(C)O)OC |
Synonyms | LY-3023414, LY 3023414 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 44 mg/mL (108.24 mM) | |
Water | Insoluble | ||
Ethanol | 57 mg/mL (140.22 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.6 mL | 123 mL | 246.01 mL |
0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2